Graphical User Interface (GUI) Development in Perl
Graphical User Interfaces (or "GUIs") are rich, graphical programs and applications that are displayed on the screen using windows, menus, buttons, input boxes, list boxes and other controls. Perl has extensive support for many GUI libraries.
wxPerl
wxPerl is a Perl interface to the open source, cross-platform wxWidgets library, which provides native look and feel, while still providing a lot of convenience.
Padre, the Perl IDE is being written using wxPerl, and one can search its source code (using ack , grep or a similar tool) to find useful examples of wxPerl code in action.
Perl-Tk
Perl-Tk is a port of the Tk toolkit that originated with Tcl, to Perl. It is cross-platform and open-source, but provides relatively unattractive widgets/controls, which are not easily skinnable. However, it provides a high-level API with many convenient niceties, and is commonly available.
Prima
Prima is a modern-looking graphical toolkit for Perl. It is cross-platform and open-source, and comes with Visual Builder (or VB for short), a graphical program to design your GUI. Prima also provides many Examples to get you started.
Perl/Qt and Perl/KDE
Perl bindings to the portable Qt library and the various libraries of KDE (the K Desktop Environment), which is written using it. The licence of the bindings is the GNU General Public License which is incompatible with many publicly distributed non-open-source and open-source licences, but using it for programs for in-house use is OK.
gtk2-perl
A set of Perl bindings for GTK and various related libraries (including those of the GNOME project). Provides an attractive look and feel on X-Window-based UNIX systems (including Linux) which looks quite foreign on Microsoft Windows. A very capable and powerful GUI library.
Note that there are perl bindings to GTK 3 made available by the same project.